Rongguang Shao Selected Research

IMB5043

1/2018

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

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Rongguang Shao Research Topics

Disease

17	Neoplasms (Cancer) 05/2022 - 01/2009
7	Breast Neoplasms (Breast Cancer) 03/2022 - 10/2003
3	Pancreatic Neoplasms (Pancreatic Cancer) 05/2022 - 01/2019
2	Lung Neoplasms (Lung Cancer) 04/2022 - 01/2019
2	Neoplasm Metastasis (Metastasis) 03/2022 - 01/2018
2	Cardiotoxicity 05/2018 - 11/2015
2	Hepatocellular Carcinoma (Hepatoma) 11/2014 - 04/2013
1	B-Cell Lymphoma (Lymphoma, B Cell) 03/2022
1	Asthma (Bronchial Asthma) 01/2020
1	Stomach Neoplasms (Stomach Cancer) 01/2020
1	Glioma (Gliomas) 01/2020
1	Colonic Neoplasms (Colon Cancer) 01/2019
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 01/2019
1	Paroxysmal nonkinesigenic dyskinesia 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2018
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2016
1	Hematologic Neoplasms (Hematological Malignancy) 01/2016
1	Trophoblastic Neoplasms (Trophoblastic Tumor) 01/2016
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2015
1	Carcinoma (Carcinomatosis) 04/2014
1	Retinoblastoma (Glioblastoma, Retinal) 02/2006

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 05/2022 - 02/2006
4	Pharmaceutical PreparationsIBA 01/2020 - 02/2006
3	Biomarkers (Surrogate Marker)IBA 05/2022 - 01/2020
3	Antineoplastic Agents (Antineoplastics)IBA 05/2018 - 11/2014
2	Biological ProductsIBA 05/2022 - 01/2016
2	LigandsIBA 01/2020 - 01/2019
2	C 1027IBA 01/2019 - 02/2006
2	Peptides (Polypeptides)IBA 01/2019 - 04/2014
2	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2016 - 11/2014
2	sophoridinolIBA 01/2016 - 11/2014
2	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 11/2015
2	MatrinesIBA 01/2016 - 11/2014
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2009 - 02/2006
1	Deubiquitinating EnzymesIBA 05/2022
1	Peptide Hydrolases (Proteases)FDA Link 05/2022
1	Messenger RNA (mRNA)IBA 05/2022
1	Cell Adhesion MoleculesIBA 05/2022
1	Transcription Factor CHOPIBA 03/2022
1	CaspasesIBA 03/2022
1	CateninsIBA 03/2022
1	Cysteine (L-Cysteine)FDA Link 01/2022
1	1,2-distearoylphosphatidylethanolamine (DSPE)IBA 01/2020
1	ClathrinIBA 01/2020
1	Zinc Finger Protein GLI1IBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Ethanolamine (Colamine)IBA 01/2020
1	Hyaluronic Acid (Hyaluronan)IBA 01/2020
1	Cytotoxins (Cytolysins)IBA 01/2019
1	ResveratrolIBA 01/2019
1	3- O- (4- O- galactopyranosyl- glucopyranosyl)- 1,2- di- O- tetradecyl- sn- glyceryolIBA 01/2019
1	ras ProteinsIBA 01/2019
1	Immunoconjugates (Immunoconjugate)IBA 01/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Topoisomerase InhibitorsIBA 05/2018
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018
1	IMB5043IBA 01/2018
1	QuinolizidinesIBA 01/2016
1	DNA TopoisomerasesIBA 11/2015
1	Cardiac GlycosidesIBA 06/2015
1	TOR Serine-Threonine KinasesIBA 06/2015
1	Adenosine Triphosphatases (ATPase)IBA 06/2015
1	Digoxin (Digitek)FDA LinkGeneric 06/2015
1	Ouabain (G Strophanthin)IBA 06/2015
1	Mitogen-Activated Protein Kinase 3IBA 06/2015
1	sophoridinic acidIBA 11/2014
1	EstersIBA 11/2014
1	Cisplatin (Platino)FDA LinkGeneric 04/2014
1	MutagensIBA 04/2014
1	U 0126 (UO 126)IBA 04/2013
1	sphingosine kinaseIBA 04/2013
1	Cyclin B1IBA 02/2006
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 02/2006
1	Estrogens (Estrogen)FDA Link 10/2003
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2003
1	Estrogen ReceptorsIBA 10/2003

Therapy/Procedure

7	Therapeutics 03/2022 - 04/2013
1	Radiotherapy 03/2022
1	Drug Therapy (Chemotherapy) 03/2022